Título

LETTERS TO THE EDITOR

REVISTA DE LA FACULTAD DE MEDICINA HUMANA 2020 - Universidad Ricardo Palma
DOI 10.25176/RFMH.v20i3.2945

EPIDEMIOLOGICAL SITUATION OF COVID-19 IN SOUTH AMERICA

SITUACIÓN EPIDEMIOLÓGICA DEL COVID-19 EN SUDAMERICA.

R. Rainer Echeverría1, J. Harumi Sueyoshi1

1Universidad Nacional Mayor de San Marcos. Lima, Perú.

Dear Editor

Currently the coronavirus (COVID-19) infection has become a public health problem worldwide. In December 2019, in the city of Wuhan, province of Hubei, China, the first cases of pneumonia of unknown etiology were reported, which incremented rapidly in other provinces of the country.(1)

Subsequently, SARS-CoV2 was identified as the causal agent and in mid-January 2020, the World Health Organization (WHO) reported over 280 confirmed cases of COVID-19 in China, Thailand, Japan and Korea.(2)

In South America, the first case of COVID-19 is made known on February 26, 2020 in the city of Sao Paulo, Brazil, identified as a male patient of 61 years of age from the region of Lombardy in Italy. Soon after there were other confirmed cases imported from the Asian and European continents in other south American countries.(3)

Up until April 14, 2020, there have been 1.983.219 COVID-19 cases reported worldwide, of which 2.84% are found in South America. Brazil is the country that has the greatest number of people infected (24,232), concentrated mainly in Sao Paulo and Rio de Janeiro. Peru is second place with 10,303 confirmed cases, with numbers multiplying in the last 5 days. This increase is affected by the number of tests performed and the lack of adherence to measures established by the government by one group of the population, causing conglomerations in the supermarkets, markets and public transport.

In Peru, men represent 73.9% of total COVID-19 confirmed cases, with the majority of those infected in the country’s capital (Lima), a tendency that is repeated in other Latin American capitals, while in Chile 50.09% of positive cases correspond to the female gender. The comorbidities identified with greater frequency in fatal cases were cardiovascular diseases (hypertension) and diabetes mellitus (Peru, Chile and Brazil). (4,5)

As far as mortality from COVID-19 in South America, Ecuador takes the lead, presenting so far, a mortality rate of 2 per 100 thousand inhabitants, followed by Peru with 0.7 per 100 thousand inhabitants.

Despite Chile being one of the South American countries that concentrates the majority of SARS-CoV2 infected people, it has the lowest fatality rate in the region (1.6%), followed by Uruguay, even lower than Japan (1.87%). This is due to the measures their authorities have taken to stop the spread of disease which includes the ability to identify infected patients and isolate them early on, a strategy that the World Health Organization has emphasized; achieving so far the greatest number of tests per million inhabitants in the region, after Venezuela. Currently Peru has adapted these measures aggressively and is the second country with greater number of diagnostic tests in Latin America, with 102,2016 between rapid tests and molecular tests. See Table 1




TABLE 1. Statistical data on COVID-19 in South America, 2020

Countries in South America

First reported case

Quarantine onset

Confirmed cases

Deaths

Fatality

Total

Tests

Tests/ Million

ARGENTINA

March 3

March 20

2,277

102

4.47%

22,805

505

BOLIVIA

March 10

March 22

354

28

7.90%

2,185

187

BRASIL

February 26

March 19 closed borders

24,232

1,378

5.68%

62,985

296

CHILE

March 3

March 18 state of emergency

7,917

92

1.16%

87,794

4,593

COLOMBIA

March 6

March 24

2,852

112

3.92%

43,053

846

ECUADOR

February 29

March 16 state of emergency

7,603

355

4.66%

25,347

1,437

PARAGUAY

March 7

March 10

159

7

4.40%

3,394

476

PERÚ

March 6

March 15

10,303

230

2.23%

102,216

3,100

URUGUAY

March 13

No quarantine

483

8

1.65%

9,236

2,659

VENEZUELA

March 13

March 17

189

9

4.76%

203,108

7,143

TOTAL

 

 

56,369

2,321

4.11%

 

 



Source: Coronavirus Resource Center Johns Hopkins University y Worldometer coronavirus. (Revised: April 14, 2020) (6,7)

Likewise, the fatality rate reflects the level of development and health system quality in each country. Despite that the health expense according to the percentage of gross domestic product in Bolivia (6.3%) is not much different than Chile (7.7%)(8),Bolivia has a higher fatality rate of 7.9% due to coronavirus, the highest in South America. This value is influenced by the lower number of diagnostic tests performed, the onset time of infection, the adopted measures by each health system and the proper characteristics of each country

With the current information. we can observe that the global figures in South American do not yet reach comparable levels to other regions such as Asia and Europe, it even seems that none have reached the level of inflection in its epidemiological curve. It is necessary to take into account that an underestimation exists regarding the reported data for each country, since this depends on the amount of screening tests that are applied in the population, furthermore, it is emphasized that the asymptomatic carriers may not be considered within the statistics, since the tests are generally conducted in symptomatic patients.

Another key for success in the control of disease spread is the responsibility and discipline of the population in following the security measures established by each government, as was demonstrated in South Korea.(9)

The spread of COVID-19 puts the health systems to the test, setting a real challenge in establishing health politics and reinforcing these, which were already deficient before the pandemic.(10) One of the greatest deficiencies that they present is the lack of personal protection equipment, availability of beds in the intensive care units and mechanical ventilators, a cornerstone in the treatment of patients with SARS-CoV2.3 infection.

It is difficult to compare numbers between nations including the adopted measures for each of them, since there exists demographic, economic and political variables that may intervene, as well as being influenced by the number of applied tests, the population density and the social context that each country experiences, factors that converts South America into a vulnerable target.(11)

It is still necessary to perform more studies to increase the stock of current knowledge.

Author contributions: The authors participated in the genesis of the idea, data collection and interpretation and manuscript preparation of the present research work.
Financing: Self-financed.
Conflict of interests: The authors declare not to have any conflict of interests.
Received: April 15, 2020
Approved: May 22, 2020


Correspondence:Echeverría Ibazeta, R. Rainer
Address: Dirección: H.H. Buenos Aires 1713 Bellavista, Callao, Perú
Telephone number: +51 970 094 986
Email: r.rainer.echeverria@gmail.com



REFERENCES

    1. Zhang G., Zhang J., Wang B., et al. Analysis of clinical characteristics and laboratory findings of 95 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a retrospective analysis. Respir Res 21, 74. 2020. DOI:
    2. Novel Coronavirus (2019-nCoV) SITUATION REPORT – 1. WHO. 2020. Disponible en: https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200121-sitrep-1-2019-ncov.pdf?sfvrsn=20a99c10_4
    3.Rodriguez A., Gallego V., Escalera J., Cimerman S., et al. COVID-19 in Latin America: The implications of the first confirmed case in Brazil, Travel Med Infect Dis. 2020. DOI: 10.1016/j.tmaid.2020.101613.
    4.Sala situacional Covid-19, Ministerio de Salud – Perú. 2020 Disponible en: https://covid19.minsa.gob.pe/sala_situacional.asp
    5.Séptimo informe epidemiológico COVID-19. Ministerio de salud de Chile Plan de acción coronavirus. 2020. Disponible en: https://www.minsal.cl/nuevo-coronavirus-2019-ncov/informe-epidemiologico-covid-19/
    6. Resource center Johns Hopkins University. Disponible en:https://coronavirus.jhu.edu/map.html
    7.Worldometer coronavirus. Disponible en:https://www.worldometers.info/coronavirus/
    9. Shim E., Tariq A., Wongyeong C., Lee Y., Chowell G., Transmission potential of COVID-19 in South Korea. Int Journal of Infect Dis. 2020. 399-344. DOI: 10.1016/j.ijid.2020.03.031
    10. Pérez J., La necesaria reforma de los Sistemas de Salud en América Latina. Gaceta Laboral. 2007,13(1) 43-57. Disponible en: http://ve.scielo.org/scielo.php?script=sci_arttext&pid=S1315-85972007000100003
    11. Rifat A., Monteiro L., Almeida G., et al. Health-system reform and universal heath coverage in Latin America. The Lancet, Volume 385, Issue 9974, 1230 - 1247. DOI: 10.1016/S0140-6736(14)61646-9


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