ABSTRACT

Diabetes is still the leading cause of non-traumatic amputation in most Western countries, epidemiological reports indicate that more than a million amputations are performed in people with diabetes each year, this is equivalent to an amputation for diabetes somewhere in the world every 30 seconds, most of these amputations are preceded by ulcers. We present a case of a 39-year-old male patient suffering from diabetes mellitus and uncontrolled hypertension, with late complications, chronic kidney disease, anemia, retinopathy, and ischemic and neuropathic diabetic foot, with indication for amputation. Healthy lifestyles are used, controlling glycemia, hypertension, without requiring medication and reducing proteinuria. There were no adverse effects. With favorable evolution since then. Conclusion: A healthy lifestyle is an intervention that the earlier it is used, the greater its benefits, without the risk of adverse effects or unnecessary costs, but even in late stages it has shown benefits in glycemic, hypertensive and renal control.

Keywords: Diabetic foot, Life style, Diabetic Nephropathy.(fuente: MeSH NLM).

RESUMEN

La diabetes sigue siendo la principal causa de amputación no traumática en la mayoría de los países occidentales⁽¹⁾, informes epidemiológicos indican que más de un millón de amputaciones se realizan en personas con diabetes cada año, esto equivale a una amputación por diabetes en algún lugar del mundo cada 30 segundos, la mayoría de estas amputaciones son precedidas por úlceras⁽²⁾. Presentamos un caso de un paciente varón de 39 años pluripatológico que padece de Diabetes Mellitus e Hipertensión no controlada, con complicaciones tardías, renal, anemia, retinopatía, y pie diabético isquémico y neuropático, con indicación de amputación. Se emplea estilos de vida saludables⁽⁶⁾, controlando glicemias, hipertensión, sin requerir medicación y disminuyendo la proteinuria. No se presentaron efectos adversos. Con evolución favorable desde entonces. Conclusión: El estilo de vida saludables es una intervención que entre más tempranamente sea empleada serán mayores sus beneficios, sin el riesgo de efectos adversos, ni costos innecesarios, pero aun en etapas tardías ha mostrado beneficios en el control glicémico, hipertensivo y renal.

Palabras Clave: Pie diabético, Estilo de Vida, Nefropatía Diabética (fuente: DeCS BIREME).

INTRODUCTION

Diabetes remains the leading cause of non-traumatic amputation in most Western countries, rates are up to 15 times higher than in the non-diabetic population ⁽¹⁾, epidemiological reports indicate that over one million amputations are performed in people with diabetes each year, this equates to one diabetic amputation somewhere in the world every 30 seconds, most of these amputations are preceded by ulcers. Only two-thirds of ulcers heal over time and the remainder may result in some form of amputation, with the average healing time for an ulcer being approximately six months. Both ulcers and amputations have a huge impact on people's lives, and often lead to dependency, social isolation and psychological stress ⁽²⁾.

PATIENT INFORMATION

Male patient, 39 years old, native from Lima, with a history of diabetes mellitus since he was 8 years old, obesity since then with BMI >40, until 10 years ago when he started to lose weight and reached a BMI 22, on treatment with Glibenclamide until 10 years ago when she started with insulin NPH 20U and metformin 850mg since 10 years ago, Arterial Hypertension 10 years ago on treatment with Nifedipine 30mg c/24h, Losartan 50mg c/12h, amputation of the 1st toe of the right foot 01/2020.

Family History: Mother, 2 sisters and maternal grandfather with diabetes mellitus.

Patient had been ill for 4 days before admission and noticed two ulcers, one in the previous surgical site and others in the plantar region, associated with foul odor and purulent discharge.

During his hospitalization the patient presents with glycemia > 400 predominantly post prandial, with indication for supracondylar amputation by medical board with the specialties of cardiovascular surgery, traumatology and internal medicine.

CLINICAL FINDINGS

PA:140/70, FC 72, FC: 62, FR 19, Sat O2: 98

Weight: 72, Height: 1.75, IMC: 22

There is evidence of hyperpigmentation of the skin, cavus foot, claw toes, widening with bony prominences in the plantar region and in the internal and external borders, ulcer at the base of the 1st metatarsal in the bed of previous surgery of 3*4cm, plantar ulcer of 3*2cm, at the base of the 3rd metatarsal with necrotic tissue, purulent secretion, bad odor, erythema, heat, edema, pain in the surrounding skin.

Decreased pedial pulses.

Fundus: Severe proliferative diabetic retinopathy in both eyes, retinal detachment.

ECODOPPLER: Mild bilateral atherothrombosis in bilateral femoral and popliteal arteries, severe atherothrombosis with diffuse lesions in infrapopliteal arteries between 50-75%.

DIAGNOSIS

- Diabetic Foot Pedis III - Neuropathic and Ischemic

- Uncontrolled Type 2 Diabetes Mellitus With Late Complications

o Non Proliferative Diabetic Retinopathy

o Diabetic Polyneuropathy

o Peripheral Arterial Insufficiency

oChronic Kidney Disease: Diabetic Nephropathy G4 A3

- Uncontrolled Arterial Hypertension

- Mild Multifactorial Anemia.

THERAPEUTIC INTERVENTION

Air: Breathing exercises, where deep thoracoabdominal breathing is strengthened, at least 10 times a day.

Rest: Sleep 7-8 hours, no later than 10pm.

Exercise: Given his condition of diabetic neuropathic foot, complicated with plantar ulcer, patient conditioned orthopedic boot, with which he exercised about 1 hour daily (bicycle) to go to work, as his means of transportation, as well as with weights (created by him) 2 times a week, especially for strengthening the upper limbs.

Food: Diet with a predominance of plants, white flour, simple sugars, fried foods, and encouraged the consumption of whole foods, vegetable proteins, polyunsaturated fats (low cost seeds, olives), omega 3 (flaxseed), fiber, salt intake was reduced, especially by avoiding the consumption of processed foods.

Water: 2 liters of water per day, maintain neutral balance.

Temperance: Avoid food between meals, no tobacco, no alcohol, no sugar.

Sunlight: 30 minutes of sun exposure

Trust in God: Daily time for meditation.

Daily healing of the foot: Water with activated charcoal for 14 minutes was prepared, then the foot was cleaned with soap and water to remove the devitalized tissue.

Family time was encouraged: The economic circumstances, added to the pandemic, isolated the family, therefore community life was encouraged, especially scheduling family visits.

Patient remains adhered to the treatment with 1 monthly follow-up, in person or by telephone, with supervision by means of photos of the food eaten, as well as of the glycemia in real time glucometer, at the beginning of treatment he presented a decrease in glycemia, without reaching symptomatic hypoglycemia, due to close control of the same, which was leveled in 2 weeks, managing to withdraw the insulin, as well as suspending the antihypertensive drugs.

Likewise, improvement of the described ulcers was evidenced.

Patient tolerated the indicated treatment, especially in the items of food, exercise, temperance, with adequate adherence, presenting glycemic control 2 weeks after discharge, without medication, as well as blood pressure control.

DISCUSSION

Diabetes remains the leading cause of non-traumatic amputation in most Western countries, rates are up to 15 times higher than in the non-diabetic population ⁽¹⁾, epidemiological reports indicate that more than one million amputations are performed in people with diabetes each year, this is equivalent to an amputation due to diabetes somewhere in the world every 30 seconds, most of these amputations are preceded by ulcers. Both ulcers and amputations have a huge impact on people's lives, and often lead to dependency, social isolation and psychological stress ⁽²⁾.

It was the therapeutic decision to amputate that led to a lifestyle change in our patient.

Diabetes is a preventable disease, as we saw in our patient suffered from obesity from an early age, as well as the family environment, which supports an important genetic load, which unfortunately shows that a late intervention in a person, no matter how young, leaves severe damage in multiple organs, however even being a late intervention it has been possible to objectify the positive impact, not only avoiding amputation, but keeping him economically active, not limiting his mobilization or economic expenses due to the disease itself.

Persistently elevated glucose has contributed unfavorably in the damage to multiple organs, such as the torpid evolution of ulcers, as well as arterial hypertension⁽³⁾.

Taking as a principle a DASH diet⁽³⁾ with a predominance of plant consumption, added to reduced sodium consumption⁽⁴⁾, especially by limiting processed foods, adequate fluid intake, these changes have had a benefit in glycemic, hypertensive⁽⁶⁾ and renal control, presenting no complications of the internal environment despite renal compromise, improving hemoglobin values, which encourages the plant-based diet, not only for its benefit in diabetes and hypertension but in renal patients, breaking old myths.

Exercise benefits not only at the cardiovascular level, but also by increasing insulin sensitivity ⁽⁷⁾.

Adequate rest ⁽⁵⁾ has reduced the consumption of harmful foods and insulin resistance; however, adherence was limited by the socio-economic context, which reduced the hours and quality of sleep, not calling into question its benefits, but encouraging greater emphasis on the emotional and spiritual aspect, which, as expressed by the WHO, has an undoubtedly positive impact on health.

No adverse effects were found that limit a healthy lifestyle even in advanced stages of the disease, but it does encourage the need for education and early interventions, which will improve quality of life, reduce health expenses, avoid complications and improve survival.

One of the challenges was the isolation during the pandemic, limiting face-to-face evaluations, especially for support in healing, so more interest was placed on patient and family education, as well as using less expensive healthy foods, exercise became part of their daily routine, which did not overload their daily work, finding a sport that is also their means of transportation.

Multidisciplinary management is necessary in these patients, given that it is a disease with multiple complications, devising new strategies, especially in this type of context should be our goal so that more patients are reached, despite the pandemic and economic limitations.

CONCLUSIONS

Healthy lifestyle is an intervention that the earlier it is employed the greater the benefits, without the risk of adverse effects or unnecessary costs, but even in late stages it has shown benefits in glycemic, hypertensive and renal control.

The limitation in lipid control was influenced by renal compromise, as the patient presented nephrotic syndrome.

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