@article{Cabrera_Peña_2020, title={Leukemia / Lymphoma T of the adult HTLV1, a challenge for the clinic: Leucemia/linfoma T del adulto HTLV1, un desafío para el clínico}, volume={20}, url={http://revistas.urp.edu.pe/index.php/RFMH/article/view/2919}, DOI={10.25176/RFMH.v20i2.2919}, abstractNote={<p>Adult T-cell leukemia/lymphoma (ATL) is an aggressive disease of mature activated T cell caused by human T-cell lymphotropic virus type 1 (HTLV-1). ATL carries a bad prognosis due to intrinsic chemoresistance and severe immunosuppression. The aggressive ATL forms, acute and lymphoma, are treated with chemotherapy associated with antiretroviral agents (AZT/IFN) the acute form. However, they have failed to achieve an impact on survival, that ranges from 8-10 months, respectively. Patients with chronic and smoldering ATL forms, have a better prognosis, but long term survival is poor as well, when these patients are managed with a watchfulwaiting policy or with chemotherapy. Apparently, AZT/IFN seams to benefit these patients. Meanwhile, prevention of dissemination of HTLV-1, is a must in public health policies, performing screening in blood banks and a screening to pregnant women to reduce/avoid vertical transmission of the virus.</p>}, number={2}, journal={Revista de la Facultad de Medicina Humana}, author={Cabrera, María Elena and Peña, Camila}, year={2020}, month={Mar.}, pages={1} }