Revista de la Facultad de Medicina Humana <p>The Revista de la Facultad de Medicina Humana (Rev. Fac. Med. Hum.) is edited by Instituto de Investigaciones en Ciencias Biomédicas of Universidad Ricardo Palma. This journal publishes original research articles in medicine and public health; adheres to the standards and recommendations of the ICMJE and COPE. It is an open access journal that is available in full text in Spanish and English.</p> <p> </p> Universidad Ricardo Palma en-US Revista de la Facultad de Medicina Humana 1814-5469 Bacterial etiology in cell phones of health personnel from a clinic in Chiclayo <p><strong>Introduction:</strong> The use of cell phones in the hospital environment is essential and at the same time constitutes a risk by acting as a reservoir and fomites for the transmission of microorganisms. <strong>Methodos</strong>: A non-probabilistic sampling was carried out on cell phones from which the sampling and enrichment were carried out according to environmental control procedures. <strong>Results:</strong> Of the 30 cell phones evaluated, 56.7% of the devices were colonized by bacteria, the most frequent being coagulase-negative Staphylococcus, S. aureus, and E. coli with 35.3% and 23.5%. <strong>Conclusion:</strong> Gram positive bacteria predominated over Gram negative ones on the surfaces of cell phones and that the percentage of contamination is due to non-compliance with good practices.</p> Alexander Alexis De la Cruz-Cueva Grescia Azucena Gonzales-Velásquez Roberto Ventura Flores Copyright (c) 2024 Revista de la Facultad de Medicina Humana 2024-05-13 2024-05-13 24 2 Quality of life and clinical characteristics of renal transplant patients with and without chronic rhinosinusitis <p><strong>Introduction: </strong>Transplantation is the treatment of choice in patients with chronic kidney disease (CKD). It requires immunosuppression, which predisposes to the development of complications. Chronic rhinosinusitis (CRS) is one of the most important.</p> <p><strong>Objective: </strong>To compare the characteristics of patients with CKD with and without CRS undergoing renal transplantation protocol in a concentration Hospital in Puebla, Mexico.</p> <p><strong>Methods: </strong>Comparative, cross-sectional, retrospective study in patients in a tertiary care hospital with CKD and undergoing renal transplantation protocol. The SNOT-22 and Lund-Mackay scales were applied. Descriptive statistics and Mann-Whitney U test, Fisher's exact test and Phi coefficient were used; p&lt;0.05 was considered significant.</p> <p><strong>Results: </strong>360 patients were recruited, 49 presented CRS, prevalence: 13.61%. Means: age: 39.22 ±12.09 years and evolution time: 17.73 ±5.91 weeks. They presented nasosinusal polyposis 14.3%, nasal obstruction 95.9%, facial algia 67.3%, rhinorrhea 49%, hyposmia/anosmia 40.8%. Associated risk factors: allergy to acetylsalicylic acid (p=0.014) and atopy (p=0.000). Anatomical variants in patients with and without CRS, respectively: Agger-Nasi cell 95% and 15.4%, septal deviation 50% and 6.4%, turbinate hypertrophy 50% and 1.3%, concha bullosa 30% and 4.2%, and turbinate paradoxical 10% and 1.6%. Predominant quality of life impairment in patients with and without CRS was moderate (53.1%) and mild (97.1%) respectively (p=0.000).</p> <p><strong>Conclusion:</strong> Prevalence of CRS was 13.61%, allergy to acetylsalicylic acid and atopy were associated risk factors; Agger-nasi was predominant anatomical variant. Tomographic severity was mild, and quality of life impairment was moderated.</p> Clotilde Margarita Andrade-Bonilla Josué Helí Flores-Figueroa Marco Andrés González-Martínez Arturo García-Galicia Álvaro José Montiel-Jarquín Diana López García Maricarmen Tapia Venancio Nancy Rosalía Bertado-Ramírez Jorge Loria Castellanos Copyright (c) 2024 Revista de la Facultad de Medicina Humana 2024-04-30 2024-04-30 24 2 10.25176/RFMH.v24i2.6209 Frequency and factors associated with mental health problems in workers vaccinated against COVID19 in a Peruvian public hospital in 2021. <p><strong>Objective:</strong> Determine the frecuency and factors associated with mental health problems in workers vaccinated against COVID19 at the Dos de Mayo National Hospital in 2021. <strong>Methods:</strong> Cross-sectional study with secondary analysis that used data from the application of the SRQ mental health questionnaire to healthcare and office workers. The evaluation was carried out prior to the third COVID19 immunization. This screening was based on the recommendations of the Ministry of Health, for the active detection of psychological disorders during the pandemic. The prevalence and odds ratios (OR) of the characteristics associated with mental health problems were calculated using logistic regression.</p> <p><strong>Results</strong>: We included 2109 workers, 62% were female, 42% were under 40 years of age and 4.6% were separated/divorced. We found a prevalence of mental health problems of 2.70% (95% CI 2.06 to 3.48). It was more frequent in women (OR: 2.30; 95% CI 1.22 to 4.76; p=0.005). Likewise, the highest prevalence was between 18 and 29 years old and between 50 and 59 years old, observing a bimodal distribution (p=0.022). There was also a higher risk in divorced/separated people (OR 3.00; 95% CI 1.12 to 7.25; p=0.019). <strong>Conclusion:</strong> One in every 40 workers who worked in person at the Dos de Mayo Hospital in October 2021 presented mental health problems. Associated factors were female sex, extreme age groups and divorced/separated marital status. The post-vaccination context would express a temporary burden of disease and would limit its use for future recommendations in different scenarios.</p> José Raúl Collantes-Schmidt Belén Virrueta-De La Sota Marlon Yovera Marco Antonio Bautista-Macedo Copyright (c) 2024 Revista de la Facultad de Medicina Humana 2024-05-13 2024-05-13 24 2 10.25176/RFMH.v24i2.6178 Clinical and epidemiological characteristics of acute pancreatitis in high altitude residents <p>Introduction. - Physiological variables that cause living at “altitude” seem to affect the characteristics of acute pancreatitis. Aim. - Describe the clinical and epidemiological characteristics of Acute Pancreatitis in high altitude residents. Materials and methods. - Epidemiological, observational, descriptive, longitudinal and retrospective study. 129 patients with Acute Pancreatitis, hospitalized from January 2017 to December 2021 at the "Daniel Alcides Carrion Hospital" located at 3,250 (masl), in Huancayo - Peru, were studied. The type of sampling was census. Results. - SaO2: 91.64%, PaO2: 68.67 mmHg, PaCO2: 29.4 mmHg, HCO3: 18.82 mEq/L, Hemoglobin: 15.51 g%, Hematocrit: 46.31%, TGO: 286.4 U/L, TGP: 313.9 U/L and Pleural effusion: 90.3%. The incidence was 38.44 cases per 10,000 hospital admissions. Mortality was 13.95%. Conclusions. - The patient with acute pancreatitis from high altitude presents lower values ​​in SaO2, PaO2, PaCO2 and HCO3 and higher values ​​in its incidence and mortality than those published at sea level.</p> Geraldine Espinoza-Mayhua Juan Amilcar Tinoco-Solorzano Copyright (c) 2024 Revista de la Facultad de Medicina Humana 2024-05-13 2024-05-13 24 2 Hypertriglyceridemia associated with insulin resistance in children with obesity <p>Objetivo: Determinar si la hipertrigliceridemia está asociada con la resistencia a la insulina en niños obesos. Material y métodos: El presente estudio es transversal, analítico y retrospectivo realizado en 58 niños obesos 6 a 14 años de edad atendidos en el consultorio externo del Departamento de Pediatría del Hospital Belén de Trujillo, durante el periodo 2014 – 2019. Los datos obtenidos fueron representados en tablas, para las variables cualitativas se utilizaron las frecuencias absolutas (n) y relativas (%), mientras que en las variables cuantitativas se emplearon medidas de tendencia central (media) y de dispersión (desviación estándar). Para identificar el factor de asociación se utilizó el coeficiente de correlación lineal de Pearson y el estadígrafo fue Odds Ratio, con un nivel de significancia 5% (p &lt; 0,05). Resultados: De los 58 participantes del estudio, un 58,6% tuvieron hipertrigliceridemia, un 74,1% mostró resistencia a la insulina. Asimismo, los niveles elevados de triglicéridos se asociaron significativamente con la presencia de resistencia a la insulina (OR = 18,91; IC 95% = 3,67 – 97,36; p = 0,00). Además, se encontró otros factores que se asociaron a la presencia de resistencia a la insulina como el nivel elevado de glicemia en ayunas, el nivel elevado de insulina en ayunas y la presencia de acantosis nigricans. Conclusiones: La hipertrigliceridemia está asociada de manera significativa con la resistencia a la insulina en niños obesos.</p> Rosario Patricia Cacha Villacorta Elena Salcedo Espejo Johnny Leandro Saavedra-Camacho Sebastian Iglesias-Osores Copyright (c) 2024 Revista de la Facultad de Medicina Humana 2024-05-13 2024-05-13 24 2 Risk factors for hyperglycemic crises in diabetic adults treated in the emergency department of a Lima hospital <p><strong>Introducción: </strong>La Diabetes Mellitus&nbsp;representa un desafío importante para la salud pública, las alteraciones hiperglucémicas son las complicaciones más serias de esta patología, pudiendo resultar en morbilidad considerable o incluso la muerte.&nbsp;<strong>Objetivo: </strong>Establecer los factores de riesgo de las crisis hiperglucémicas en adultos diabéticos atendidos en la unidad de emergencia de un Hospital General de Lima.<strong>&nbsp;Métodos: </strong>Estudio analítico tipo casos y controles, realizado en un hospital de Lima, durante enero 2015 a diciembre 2019, en una población de 3580 historias clínicas. Los criterios de inclusión fueron:&nbsp;historias clínicas sean legibles y que presentaran datos completos. Para el análisis bivariado se utilizó Chi Cuadrado y la prueba exacta de Fisher. Para el análisis multivariado se aplicó la regresión logística. Se utilizó el Odds Ratio crudo (ORc) y ajustado (ORa), con intervalos de confianza de 95% (IC95%) y se empleó un nivel de significancia p &lt; 0,05.<strong>&nbsp;Resultados: </strong>En el análisis bivariado los factores que se asociaron con las crisis hiperglucémicas fueron; el sexo (p=0,029), edad (p=0,000), tiempo de enfermedad (p=0,001) y adherencia a la medicación (p=0,000). No se halló relación con las variables residencia, seguro de salud, procesos infecciosos agudos y comorbilidades (p&gt;0,05). En el análisis multivariado los factores que influyen en las crisis hiperglucémicas fueron la edad (OR=2,854 IC: 1,408 – 5,785, p=0,004), y adherencia a la medicación (OR=3,874 IC: 1,835 – 8,176, p=0,000). Conclusión<strong>: </strong>Los factores de riesgo de las crisis hiperglucémicas; son la edad y la no adherencia a la medicación.</p> Madeleine Lopez Bautista Daniel Angel Cordova Sotomayor Copyright (c) 2024 Revista de la Facultad de Medicina Humana 2024-05-13 2024-05-13 24 2 Body Mass Index and Blood Pressure in Urban Adolescents in Mexico <p><strong>Introduction:</strong> The changes made by the COVID-19 pandemic in its activities have also affected recreational issues due to the limitation of contact in order to avoid the spread of the virus. This has contributed to increase the overweight and obesity indicators. <strong>Objective:</strong> Determine the association degree between Body Mass Index and systemic blood pressure in teenagers. <strong>Methods:</strong> Measurement of these variables was performed continuously for 24 hours without interruption. The sample consisted of 53 high school students with urban geographic characteristics in Mexico. All participants were evaluated anthropometrically in order to identify remarkable characteristics of the group. <strong>Results:</strong> Of the 42 patients included, about 28.5% showed obese, 21.45% showed overweight and no patient had systemic arterial hypertension; however, 23.8% showed prehypertension, directly proportional correlation of BMI with systolic and diastolic blood pressure Spearman's Rho values of 0.390 and 0.382, respectively. <strong>Conclusion:</strong> The data allow to identify a significant association between the variables BMI and BP.</p> Rodolfo Delgadillo Castañeda Copyright (c) 2024 Revista de la Facultad de Medicina Humana 2024-05-13 2024-05-13 24 2 Use of Headphones and Hearing in Medical Students at a Public University in Lima, Peru <h1>Introduction: Hearing consists of the ability of human beings to hear sounds. Inappropriate use of headphones for long periods of time and at high intensity can cause damage to the hair cells of the inner ear, resulting in a generally irreversible hearing loss known as sensorineural hearing loss. Objective: To determine the relationship between the use of headphones and hearing in medical students at a public university in Lima. Method: A quantitative, correlational, non-experimental and cross-sectional study; the sample consisted of 98 medical students from the Universidad Nacional Federico Villarreal; the data collection instrument consisted of 19 items related to the variables use of headphones and hearing. The relationship between the variables was analysed using Spearman's Rho correlation coefficient. Results: The study corresponded to 98 people between the ages of 18 and 32 years, with 59.20% being female. 52.04% of cases presented mild hearing loss to acute tones, the time of exposure to the use of headphones predominates from 1 to 2 continuous hours in 30.61% of people, on the other hand, 28.57% of students use headphones at high volume. When analysing the symptoms of hearing loss with the use of headphones, 46.94% have tinnitus, 41.84% feel hearing loss, 56.12% have otalgia and 71.43% feel that their hearing has decreased. In the inferential analysis using Spearman's correlation coefficient, we found a positive correlation between the use of headphones and hearing with a value of 0.298; likewise, when correlating exposure time and sound intensity with hearing, there was a positive correlation.</h1> <h1>Conclusion: There is a direct positive relationship between the use of headphones and hearing in medical students at the Universidad Nacional Federico Villarreal.</h1> <h1>Keywords: Hearing loss, hearing loss, hearing aid use, hearing aids, hearing loss.</h1> Félix Cordero-Pinedo Leydy Cordero Filomeno Jauregui Jorge Astocondor Copyright (c) 2024 Revista de la Facultad de Medicina Humana 2024-05-13 2024-05-13 24 2 Perception of the Organizational Climate and Safety Culture in the Surgery Service of a Level III-1 Emergency Hospital <p><strong>Introducción:</strong> El grado de madurez de un sistema de salud, se relaciona con su clima organizacional y como esta influye en las medidas de seguridad en beneficio tanto del personal asistencial como de los pacientes. <strong>Objetivo:</strong> determinar la relación entre la cultura de seguridad y el clima organizacional en el personal de salud del área de cirugía de emergencias de un hospital de emergencias nivel III-1. <strong>Materiales y métodos:</strong> Estudio observacional, prospectivo, y transversal. Se emplearon los cuestionarios MOSPS y ECOS-S para medir la cultura de seguridad y el clima organizacional respectivamente en 100 profesionales de la salud del área de cirugía de emergencias del hospital José Casimiro Ulloa. Se realizo el análisis empleando la prueba de correlación de Spearman. <strong>Resultados</strong>: La percepción del clima organizacional es de adecuado con (43%) frente a una cultura de seguridad de nivel medio (82%), se corrobora una relación positiva de magnitud moderada entre ambas, por arrojar un coeficiente de Rho de Spearman igual a 0,501, junto a un p-valor inferior al 0,05. Se afirma la hipótesis sometida al análisis, y se encuentra una asociación positiva entre la cultura de seguridad y las dimensiones de clima organizacional, comportamiento organizacional (rho spearman = 0,479), estructura organizacional (rho spearman = 0,477) y estilo de dirección (rho spearman = 0,444) todos con un p menor 0,000. <strong>Conclusiones:</strong> Existe una relación positiva entre la cultura de seguridad del personal de salud del servicio de cirugía de emergencias.</p> <p><strong>Palabras clave:</strong> Medidas de Seguridad, Cultura Organizacional, Personal de Salud, Servicio de Cirugía en Hospital. (Fuente: DeCS- BIREME)</p> Robert Ricardo Vega Vega Luis Enrique Podestá Gavilano Copyright (c) 2024 Revista de la Facultad de Medicina Humana 2024-05-13 2024-05-13 24 2 Pulmonary Aspergillosis: A Case Series on Clinical and Radiological Manifestations <p><strong>Background: </strong>Pulmonary Aspergillosis is an infection caused by fungi of the genus <em>Aspergillus</em>, an example of an opportunistic pathogen mainly affecting immunocompromised patients and associated with high morbidity and mortality. Therefore, its incidence is low. Clinical manifestations are nonspecific, so diagnostic categories have been established, including host factors, traditional mycological laboratory, and biomarkers. These, plus a better understanding and interpretation of the tomographic images, allow the clinician to offer adequate management.</p> <p><strong>Methods: </strong>The following are 3 cases of patients with pulmonary aspergillosis and their radiological features.</p> <p><strong>Case series: </strong>Three clinical cases of patients with heterogeneous characteristics sharing immunosuppression as the only risk factor are presented. The diagnosis and the clinical and radiological manifestations are also presented.</p> <p><strong>Conclusions: &nbsp;</strong>Knowing the different diseases that can appear in immunosuppressed patients is crucial since it is challenging for the clinician, given the high morbidity. It is part of the clinician's criterion to be able to suspect to diagnose and treat.</p> <p><strong>MeSH keywords: </strong>Aspergillus, Colombia, computed axial lung tomography, pulmonary aspergillosis.</p> Onaldo José Barrios Taborda Jhon Edward Valencia Marulanda Luisa Fernanda Sierra Garzón Andrés Alirio Restrepo Bastidas Mateo Aguirre Flórez Ángela María Giraldo Montoya Copyright (c) 2024 Revista de la Facultad de Medicina Humana 2024-05-13 2024-05-13 24 2 Challenges and advances in metastatic non-small cell lung cancer with mutated EGFR <p>Tyrosine kinase inhibitors have dramatically changed the clinical outcomes for patients with advanced non-small cell lung cancer with epidermal growth factor receptor mutations. However, there are still challenges in the management of patients with this mutation in a metastatic setting, such as intrinsic and acquired resistance to tyrosine kinase inhibitors. We will discuss the latest advances and new strategies in first-line treatment, osimertinib resistance, and exon 20 mutation treatment.</p> Melanie Castro-Mollo Rossana Ruiz Katia Roque Luis Mas Copyright (c) 2024 Revista de la Facultad de Medicina Humana 2024-04-30 2024-04-30 24 2 10.25176/RFMH.v24i2.6441 Review on teenage pregnancy and its social consequences <p>The purpose of this research is to establish the different methods of preventing early pregnancy in adolescents between 10 and 19 years of age in Latin America. In this project, the PRISMA method was applied using articles searched in the PubMed database, categorizing them in an age range of 10 to 19 years, the region of the investigation and the year of publication of the article, which should have been published from of 2010. It was identified that the main reasons for adolescent pregnancies in Latin America are: lack of sexual education, socioeconomic inequalities, lack of use of contraceptive methods, among others. This indicates that the possible solution to this great social problem could be to promote the sexual education campaign for children and adolescents.</p> Milena Cevallos Mendoza Arelis Lilibeth Moreira Burgos Sofía Burga Guambiango Mayte Betsabe Chiluisa Peñaherrera Andrea Jusmely Zamora Cedeño Copyright (c) 2024 Revista de la Facultad de Medicina Humana 2024-05-13 2024-05-13 24 2