TY - JOUR AU - Quiñones-Laveriano, Dante Manuel AU - Soto, Alonso AU - Quilca-Barrera, Lucero PY - 2021/05/19 Y2 - 2024/03/29 TI - Frequency of coinfection by respiratory pathogens and its impact on the prognosis of patients with COVID-19.: Frecuencia de coinfección por patógenos respiratorios y su impacto en el pronóstico de pacientes con COVID-19. JF - Revista de la Facultad de Medicina Humana JA - Rev.Fac.Med.Hum VL - 21 IS - 3 SE - Review article DO - 10.25176/RFMH.v21i3.3520 UR - https://revistas.urp.edu.pe/index.php/RFMH/article/view/3520 SP - AB - <div><strong>Introduction:&nbsp;</strong>Co-infection between other microorganisms and SARS-CoV-2, such as viruses, bacteria&nbsp;and fungi, is an important factor in the management of COVID-19, which could increase the difficulties&nbsp;in diagnosis, management, prognosis, and even increase the mortality.&nbsp;<strong>Objectives:&nbsp;</strong>The objective of this&nbsp;review is to describe the published scientific evidence regarding coinfection in patients with COVID-19.&nbsp;<strong>Methods:&nbsp;</strong>A bibliographic search of studies published in Spanish or English was carried out using the&nbsp;PubMed, The Cochrane Library and Google Scholar search engines. Studies published between January</div><div>2020 and January 24, 2021 were assessed.&nbsp;<strong>Results:&nbsp;</strong>25 articles from various continents (America, Asia and&nbsp;Europe) were included. All the studies had patients with a confirmed diagnosis of COVID-19 added to some&nbsp;other test that identified some co-infection. We identified 18 studies that showed bacterial coinfection,&nbsp;17 studies of viral coinfection and 5 studies of fungal coinfection. The prevalence of coinfection showed&nbsp;extremely dissimilar figures according to the population studied and diagnostic criteria.&nbsp;<strong>Conclusions:&nbsp;</strong>The</div><div>presence of coinfection seems to be linked to a higher frequency of unfavorable outcomes. However, it&nbsp;is important to develop Latin American studies, given the heterogeneity in the studies seen in different&nbsp;countries. Standardized definitions should be developed in order to be able to assess the impact of co-infections in patients with a diagnosis of COVID-19</div> ER -