EVALUATION OF CLINICAL ASPECTS RELATED TO LOWER LIMB AMPUTATION AMONG INDIVIDUALS LIVING WITH TYPE 2 DIABETES MELLITUS IN MEXICO: EVALUACIÓN DE ASPECTOS CLÍNICOS RELACIONADOS CON LA AMPUTACIÓN DE MIEMBROS INFERIORES EN PERSONAS QUE VIVEN CON DIABETES MELLITUS TIPO 2 EN MÉXICO

Julio Cesar Parra Acosta; Laura Ávila Jiménez; Antonio Monroy Noyola; Diana Lizbeth Gómez Galicia; Daniel Álvarez Escobedo; Cairo Toledano Jaimes

doi:10.25176/RFMH.v23i4.5980

Authors

Julio Cesar Parra Acosta Universidad Atuónoma del Estado de Morelos https://orcid.org/0000-0002-0577-9178
Laura Ávila Jiménez Jefatura de Servicios y Prestaciones Médicas, Instituto Mexicano del Seguro Social, Cuernavaca, Morelos. México.
Antonio Monroy Noyola Hospital General Regional con Medicina Familiar No.1, Instituto Mexicano del Seguro Social, Morelos. México.
Diana Lizbeth Gómez Galicia Facultad de Farmacia. Universidad Autónoma del Estado de Morelos. México
Daniel Álvarez Escobedo Hospital General Regional con Medicina Familiar No.1, Instituto Mexicano del Seguro Social, Morelos. México
Cairo Toledano Jaimes Facultad de Farmacia. Universidad Autónoma del Estado de Morelos. México.

DOI:

https://doi.org/10.25176/RFMH.v23i4.5980

Keywords:

diabetes, glycemic, glycated hemoglobin, amputation, pharmacotherapy, control glicémico, amputaciones

Abstract

Introduction: Diabetes continues to be one of the leading causes of disability and death in the global population. It is estimated that approximately 25% of people living with diabetes will develop an ulcer on one of their lower pelvic limbs.

Objective: The present study evaluates the clinical aspects related to lower pelvic limb amputation in a cohort of patients with diabetes mellitus.

Materials and Methods: A retrospective cross-sectional study was conducted consisting in a review of the total census of patients with type 2 diabetes. They received medical attention in the setting of the study in the period January-May 2022. According to the ICD-10 a total of 2021 patients with multiple complications of diabetes were identified through their clinical records. One hundred patients were diagnosed with diabetic foot.

Results: Degree of average glycemic control in the 6 months following diagnosis of diabetic foot was a relevant variable. Since patients with optimal glycemic control by quantifying their fasting glucose levels (<130 mg/dl) as well as their glycated hemoglobin values (< 7%), had a less frequency of amputations (p˂0.001; Chi²) compared to those patients without an adequate glycemic control.

Conclusions: After the analysis conducted in the population, it was found that being male, having glycated hemoglobin values higher than 7%, and having average fasting glucose values higher than 130 mg/L increase the probability of presenting a lower extremity amputation.

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Author Biographies

Julio Cesar Parra Acosta, Universidad Atuónoma del Estado de Morelos

Maestría en Farmacia.

Laura Ávila Jiménez, Jefatura de Servicios y Prestaciones Médicas, Instituto Mexicano del Seguro Social, Cuernavaca, Morelos. México.

Doctorado en Ciencias

Antonio Monroy Noyola, Hospital General Regional con Medicina Familiar No.1, Instituto Mexicano del Seguro Social, Morelos. México.

Doctorado en Neurociencias.

Diana Lizbeth Gómez Galicia, Facultad de Farmacia. Universidad Autónoma del Estado de Morelos. México

Doctora en Farmacia (Dra. en F.)

Daniel Álvarez Escobedo, Hospital General Regional con Medicina Familiar No.1, Instituto Mexicano del Seguro Social, Morelos. México

Maestría en Ciencias de la Salud (M. en CS.)

Cairo Toledano Jaimes, Facultad de Farmacia. Universidad Autónoma del Estado de Morelos. México.

Doctora en Farmacia (Dra. en F.)

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