Rhinoscleroma as a differential diagnosis of mucormycosis: A case repor

Rinoescleroma como diagnóstico diferencial de mucormicosis: reporte de caso

Authors

  • Julio C. Layseca-Ortiz Hospital María Auxiliadora. Lima, Perú.
  • Juan Manuel Combe-Fernandez Hospital María Auxiliadora. Lima, Perú.
  • Angela Gabriela Vasquez-Leon Hospital María Auxiliadora. Lima, Perú.
  • Jorge Roberto Mosqueira-Sanchez Departamento de Medicina Interna, Clínica San Pablo. Lima, Perú. Hospital María Auxiliadora https://orcid.org/0000-0002-3578-8323

DOI:

https://doi.org/10.25176/RFMH.v2025i1.6436

Abstract

Rhinoscleroma is a chronic granulomatous disease rare in our country but endemic in various parts of the world, covering regions of North Africa, Middle East, Central America, is caused in most cases by Klebsiella rhinoscleromatis affecting mainly the nasal cavity and nasopharynx, the presentation is more common in upper respiratory tract. Symptoms occur months after infection and depend on the stage of infection, these can be: fetid rhinorrhea, nasal obstruction, nasal deformity, destruction of nasal cartilage. The diagnosis is anatomopathological where Mikulicz cells are evidenced. The treatment of rhinoscleroma is with antibiotics for a prolonged period (2-3 months), in cases of airway obstruction surgical intervention should be performed.

We present the case of a 60-year-old woman with a history of diabetes mellitus type 2 and arterial hypertension, who arrives at the hospital with a pathological anatomy report showing thin and septate hyphae, suggestive of infection by Mucor. Subsequent hospital biopsy ruled out mucormycosis and confirmed the diagnosis of rhinoscleroma.

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Author Biographies

Julio C. Layseca-Ortiz, Hospital María Auxiliadora. Lima, Perú.

Residente de Medicina Interna

Juan Manuel Combe-Fernandez, Hospital María Auxiliadora. Lima, Perú.

Médico Internista

Angela Gabriela Vasquez-Leon, Hospital María Auxiliadora. Lima, Perú.

Medica Interna

Jorge Roberto Mosqueira-Sanchez, Departamento de Medicina Interna, Clínica San Pablo. Lima, Perú. Hospital María Auxiliadora

Médico Internista

Published

2025-03-31

How to Cite

Layseca-Ortiz, J. C. ., Combe-Fernandez, J. M. ., Vasquez-Leon, A. G. ., & Mosqueira-Sanchez, J. R. (2025). Rhinoscleroma as a differential diagnosis of mucormycosis: A case repor: Rinoescleroma como diagnóstico diferencial de mucormicosis: reporte de caso. Revista De La Facultad De Medicina Humana, 2025(1). https://doi.org/10.25176/RFMH.v2025i1.6436