Consumo de tabaco y Neoplasia Intraepitelial Cervical: Tobacco Use and Cervical Intraepithelial Neoplasia

Noemí Rojas Cisneros; Rony Ruíz Saucedo

doi:10.25176/RFMH.v21i1.3401

Authors

Noemí Rojas Cisneros https://orcid.org/0000-0002-2387-7863
Rony Ruíz Saucedo https://orcid.org/0000-0002-7577-2035

DOI:

https://doi.org/10.25176/RFMH.v21i1.3401

Keywords:

Cervical intraepithelial neoplasia, Tobacco use, Smoking, Smoking women, Lifestyle Medicine

Abstract

Objective: To determine the effect of tobacco consumption with the development in women of cervical intraepithelial neoplasia. Methods: A systematic review was conducted. The electronic search was carried out, using the research question: What is the association between smoking and the development of cervical intraepithelial neoplasia? whose PEO question was: Population: Women. Exposure: Tobacco use. Outcome: Cervical intraepithelial neoplasia. Articles published from January 1, 2014 to December 2019 were selected. Results: 71 articles were found, 55 being excluded because they did not meet the selection criteria, leaving 16 articles for this paper analysis. Those women who smoked tobacco had a significant association for the development of high-grade intraepithelial neoplasia (OR = 1.43, 95% CI = 1.14-1.80). Likewise, synergy was observed between severe smoking and the use of oral contraceptives, with a greater risk of grade II and III intraepithelial neoplasia (OR = 11.5; 95% CI, 1.88-70.40). Conclusion: The available evidence suggests the association between tobacco use and the development of cervical intraepithelial neoplasia, particularly high-grade cervical intraepithelial lesions.