Factores asociados al incumplimiento de la vacunación infantil de difteria, pertussis y tétanos en Perú, año 2019: Factors associated with the non-compliance of the child vaccination of diphtheria, pertussis and tetanus in Peru, year 2019

Bryan A. Aquino-Sosa; Lucy Correa-Lopez; Maria Loo-Valverde; María del Socorro Alatrista Gutiérrez Vda. de Bambarén; Norka R. Guillén-Ponce

doi:10.25176/RFMH.v22i2.4775

Authors

Bryan A. Aquino-Sosa Universidad Ricardo Palma, Lima-Perú https://orcid.org/0000-0001-8801-2302
Lucy Correa-Lopez Universidad Ricardo Palma, Lima-Perú https://orcid.org/0000-0001-7892-4391
Maria Loo-Valverde Hospital Nacional Edgardo Rebagliati Martins https://orcid.org/0000-0002-8748-1294
María del Socorro Alatrista Gutiérrez Vda. de Bambarén
Norka R. Guillén-Ponce Universidad Ricardo Palma, Lima-Perú https://orcid.org/0000-0001-5298-8143

DOI:

https://doi.org/10.25176/RFMH.v22i2.4775

Keywords:

DPT vaccine, Immunization, Public health, Breach

Abstract

Introduction:Pertussis tetanus and diphtheria, (DPT) are highly contagious diseases in children; worldwide vaccination schemes have been established for the prevention of these pathologies. However, different factors can lead to non-compliance with them.

Objective: To determine the factors associated with non-compliance with the vaccination schedule against diphtheria,pertussis and tetanus(DPT) in Peru in2019.

Methods:Analytical, retrospective study of secondary source based on data from 7 187 mothers between 15 and 49 years old regarding the vaccination schedule of their children older than six months of age obtained in the Demographic and Family Health Survey (ENDES) Peru 2019.The vaccination schedule of children over six months of age and the sociodemographic variables of the mothers were analyzed. A bivariate and multivariate analysis was performed using the chi square test for independence (p<0,050).

Results:The sample included in the study was 7 187 mothers surveyed regarding the vaccination schedule for their children older than six months of age. The variables associated with the incomplete scheme by multivariate analysis were: low educational level (RPa: 1,19; 95% CI: 1,02-1,40), not having health insurance (RPa: 1,41; 95% CI: 1,23-1,60), wealth index poor (RPa:1,19; CI95%: 1,02-1,40), age of the mother under 20 years (PR:2,63; CI95%:2,06-3,35) and having two or more children (PRa:1,36; CI95%:1,19 -1,57).

Conclusion: The index factors of wealth, mother's age, low educational level, not having health insurance and having more than two children are associated with non-compliance with the DPT vaccination schedule.

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References

Nieves DJ, Heininger U. Bordetella pertussis. Microbiol Spectr. 2016;4(3).

Pertussis | Whooping Cough | Surveillance | Cases by Year | CDC [Internet]. 2020 [citado 6 de diciembre de 2020]. Disponible en: https://www.cdc.gov/pertussis/surv-reporting/cases-by-year.html

Finkelstein P, Teisch L, Allen CJ, Ruiz G. Tetanus: A Potential Public Health Threat in Times of Disaster. Prehospital Disaster Med. junio de 2017;32(3):339-42.

Liang JL, Tiwari T, Moro P, Messonnier NE, Reingold A, Sawyer M, et al. Prevention of Pertussis, Tetanus, and Diphtheria with Vaccines in the United States: Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep Morb Mortal Wkly Rep Recomm Rep. 27 de 2018;67(2):1-44.

Sharma NC, Efstratiou A, Mokrousov I, Mutreja A, Das B, Ramamurthy T. Diphtheria. Nat Rev Dis Primer. 05 de 2019;5(1):81.

Minsa toma medidas de control frente a casos de difteria en Lima [Internet]. [citado 2 de diciembre de 2020]. Disponible en: https://www.gob.pe/institucion/minsa/noticias/312601-minsa-toma-medidas-de-control-frente-a-casos-de-difteria-en-lima

La Nación / Difteria en Paraguay: instan a la vacunación tras brote en países de la región [Internet]. [citado 4 de diciembre de 2020]. Disponible en: https://www.lanacion.com.py/pais/2020/11/05/difteria-en-paraguay-instan-a-la-vacunacion-tras-brote-en-paises-de-la-region/

Resolución Ministerial N° 719-2018/MINSA [Internet]. [citado 27 de septiembre de 2020]. Disponible en: https://www.gob.pe/institucion/minsa/normas-legales/178240-719-2018-minsa

Peck M, Gacic-Dobo M, Diallo MS, Nedelec Y, Sodha SV, Wallace AS. Global Routine Vaccination Coverage, 2018. MMWR Morb Mortal Wkly Rep. 25 de 2019;68(42):937-42.

Luna-Casas G, Juliao P, Carreño-Manjarrez R, Castañeda-Prado A, Cervantes-Apolinar MY, Navarro-Rodriguez R, et al. Vaccine coverage and compliance in Mexico with the two-dose and three-dose rotavirus vaccines. Hum Vaccines Immunother. 2019;15(6):1251-9.

Gilbert NL, Gilmour H, Wilson SE, Cantin L. Determinants of non-vaccination and incomplete vaccination in Canadian toddlers. Hum Vaccines Immunother. 03 de 2017;13(6):1-7.

Lernout T, Theeten H, Hens N, Braeckman T, Roelants M, Hoppenbrouwers K, et al. Timeliness of infant vaccination and factors related with delay in Flanders, Belgium. Vaccine. 3 de enero de 2014;32(2):284-9.

Salmon DA, Dudley MZ, Glanz JM, Omer SB. Vaccine hesitancy: Causes, consequences, and a call to action. Vaccine. 27 de noviembre de 2015;33 Suppl 4:D66-71.

Burton A, Monasch R, Lautenbach B, Gacic-Dobo M, Neill M, Karimov R, et al. WHO and UNICEF estimates of national infant immunization coverage: methods and processes. Bull World Health Organ. julio de 2009;87(7):535-41.

Cobertura vacunal [Internet]. [citado 7 de diciembre de 2020]. Disponible en: https://www.who.int/es/news-room/fact-sheets/detail/immunization-coverage

Teleconferencias semanales: Cobertura de vacunación Perú 2019. [Internet]. CDC MINSA. [citado 6 de diciembre de 2020]. Disponible en: https://www.dge.gob.pe/portal/docs/tools/teleconferencia/2019/SE022019/04.pdf

Guillermo Alvarez SA, Huarca Apaza DE. Características sociodemográficas y cumplimiento del esquema de vacunación en niños menores de 2 años en el Centro de Salud Perú III Zona – San Martín de Porres de Enero a Marzo 2018. Univ Priv Norbert Wien [Internet]. 29 de noviembre de 2018 [citado 26 de septiembre de 2020]; Disponible en: http://repositorio.uwiener.edu.pe/handle/123456789/2659

Valenzuela MT. Importancia de las vacunas en salud pública: hitos y nuevos desafíos. Rev Médica Clínica Las Condes. 1 de mayo de 2020;31(3):233-9.

Scheepers ED, van Lier A, Drijfhout IH, Berbers G, van der Maas NAT, de Melker HE, et al. Dutch national immunization schedule: compliance and associated characteristics for the primary series. Eur J Pediatr. junio de 2017;176(6):769-78.

Hadjipanayis A, Efstathiou E, Michaelidou K, Papaevangelou V. Adherence to pneumococcal conjugate vaccination schedule and uptake rate as compared to the established diphtheria-tetanus-acellular pertussis vaccination in Cyprus. Vaccine. 11 de 2018;36(38):5685-91.

Tauil M de C, Sato APS, Waldman EA. Factors associated with incomplete or delayed vaccination across countries: A systematic review. Vaccine. 23 de 2016;34(24):2635-43.

Kagoné M, Yé M, Nébié E, Sie A, Schoeps A, Becher H, et al. Vaccination coverage and factors associated with adherence to the vaccination schedule in young children of a rural area in Burkina Faso. Glob Health Action [Internet]. 29 de noviembre de 2017 [citado 1 de noviembre de 2020];10(1). Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800485/

Kusuma YS, Kumari R, Pandav CS, Gupta SK. Migration and immunization: determinants of childhood immunization uptake among socioeconomically disadvantaged migrants in Delhi, India. Trop Med Int Health. 2010;15(11):1326-32.

Francis MR, Nuorti JP, Kompithra RZ, Larson H, Balraj V, Kang G, et al. Vaccination coverage and factors associated with routine childhood vaccination uptake in rural Vellore, southern India, 2017. Vaccine. 21 de 2019;37(23):3078-87.

Kurosky SK, Davis KL, Krishnarajah G. Completion and compliance of childhood vaccinations in the United States. Vaccine. 12 de enero de 2016;34(3):387-94.

Yismaw AE, Assimamaw NT, Bayu NH, Mekonen SS. Incomplete childhood vaccination and associated factors among children aged 12–23 months in Gondar city administration, Northwest, Ethiopia 2018. BMC Res Notes. 29 de abril de 2019;12(1):241.

Chuquin E. Variables sociodemográficas asociadas al incumplimiento del esquema básico de vacunación en menores de 5 años en perú durante el año 2017 [Internet]. [Lima]: Universidad Ricardo Palma; 2019. Disponible en: https://repositorio.urp.edu.pe/bitstream/handle/URP/2212/ACHUQUIN.pdf?sequence=1&isAllowed=y

Vásquez-Uriarte K, Ninatanta Ortiz JA, Romani F, Roque-Henriquez JC. Cobertura y factores asociados a la vacunación contra el sarampión en niños de 12 a 59 meses en Perú: estimación basada en la Encuesta Demográfica y de Salud Familiar 2017. Rev Peru Med Exp Salud Publica. octubre de 2019;36(4):610-9.

Khan J, Shil A, Prakash R. Exploring the spatial heterogeneity in different doses of vaccination coverage in India. PLoS ONE [Internet]. 28 de noviembre de 2018 [citado 1 de noviembre de 2020];13(11). Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261550/

Hoz F de la, Perez L, Wheeler JG, Neira M de, Hall AJ. Vaccine coverage with hepatitis B and other vaccines in the Colombian Amazon: do health worker knowledge and perception influence coverage? Trop Med Int Health. 2005;10(4):322-9.