Terapia de estrógenos vaginales y riesgo de recurrencia en mujeres con antecedente de cáncer de mama
Vaginal estrogen therapy and the risk of recurrence in women with a history of breast cancer
DOI:
https://doi.org/10.25176/RFMH.v23i3.5692Palabras clave:
Estrógenos, Cremas, espumas y gelatinas vaginales, Neoplasias Mamarias, Factores de Riesgo, RecurrenciaResumen
El cáncer de mama sigue siendo la neoplasia maligna más frecuente y mortal en mujeres, considerándose un importante objetivo de la salud global y prioridad en salud pública. Con el uso de terapias innovadoras, ha mejorado la supervivencia, apareciendo condiciones asociadas, como el síndrome genitourinario menopaúsico. La terapia hormonal, se utiliza para el manejo de esta condición, mejorando sustancialmente la sintomatología, e incluso, siendo en algunos casos la única solución. La más utilizada, es la terapia de estrógenos vaginales. Sin embargo, se ha descrito un posible riesgo de recurrencia de cáncer de mama con su uso. En habla hispana, no existe evidencia que haya discutido este tópico. Se llevó a cabo una búsqueda en las bases PubMed, ScienceDirect y MEDLINE, utilizando los términos “Terapia de estrógenos vaginales”, “Recurrencia” y “Cáncer de mama”. Se encontró, que, de forma global, la terapia de estrógenos vaginales es una opción terapéutica eficaz y segura en el manejo del síndrome genitourinario menopaúsico en mujeres con antecedente de cáncer de mama, sin incrementar el riesgo de recurrencia, a excepción de aquellas tratadas con inhibidores de la aromatasa, en quienes se recomienda el uso de otras terapias para evitar acarrear este riesgo.
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Derechos de autor 2023 Revista de la Facultad de Medicina Humana
Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.
